Variable-rate irrigation (VRI) has the potential to increase yields and reduce water consumption and energy costs. Spatial and temporal variability of soil and field properties can impact the efficiency of irrigation and crop yield. The VRI technology allows for the precise application of irrigation to meet crop water demands in controlled amounts prescribed for specific management zones within a field. Sensitivity to over and under-irrigation and the high-water requirements of potato make the crop a good candidate for site-specific irrigation management. The use of VRI to conserve water and obtain high quality potato production was tested in Southern Alberta, Canada during the 2015 and 2016 growing seasons. Exceptionally dry weather in 2015 resulted in a total of 21 irrigation events. Overall, 43% less water was applied under the VRI, and a 12% reduction in irrigation pumping cost was achieved. The crop in plots receiving normal irrigation (361 mm per season) produced a slightly lower yield than plots receiving high irrigation (480 mm per season) but produced the best quality in terms of uniformity of size and glucose content of the tubers. In 2016, there were no significant differences between potato yield and quality within the irrigation treatments due to significant amounts of precipitation during the growing season.