Soil available nutrients are the key determinants in crop growth, field stable output and ecological balance. The soil nutrients loss and surplus can strongly influence the stability of field ecological environment and cause unnecessary pollution. Hence, optimizing the status of soil available nutrients status has significant ecological and economic significance. With the advancement of mechanized farming and control technologies, soil available nutrients can be optimize by variable rate fertilization. The effective and stable soil available nutrients variation simulation of the entire region in a large time-span is necessary before the corresponding control measures can be applied. However, the base soil available nutrients are usually variable between and within growth season, making common methods impossible to simulate the temporal and spatial variation with the required precision. Thus in this study, we introduce a new method to map soil available nutrients by integrating the crop model and time series remote sensing data. We select the World Food Studies (WOFOST) and time series HJ-1 CCD data to retrieve the soil available nutrients variation in Shuangshan farm, Northeast China. And the spatial heterogeneity can be effectively estimated within the growth season. Because the farm is implementing uniform fertilization management through last 5 years, the temporal variation can also be simulated using transformation algorithms. The soil available nutrients contents were simulated and analyzed in two ways. Firstly, we applied the simulation method to the study area in recent five years to monitor the inter-annual variation and analyzed the variation inducement. The results indicated that crop growth and precipitation intensity can both bring variations between years and plots. The within-year variation was also analyzed by estimating the soil available nutrients contents of the whole growth season with the step of five days which showed that the nutrients contents presented downtrend basically while the variation can be quite different among plots. In general, the temporal and spatial variation of soil available nutrients under uniform fertilization condition can be simulated with high stability and accuracy. Appropriate fertilization measures can also be developed to protect field ecological environment based on the analysis of simulation results.