This presentation will disclose results of a study of yearly change of key soil properties in response to variable rate application of mineral fertilizers while cultivating different crops under different climatic conditions. These experiment were conducted across several fields in Northern Ukraine. In each field, annual systematic soil sampling and analysis was conducted using the same sampling locations and analytical procedure. Prescription maps were developed using interpolated thematic soil maps and applied using bad placement of fertilizers. This presentation illustrate year-to-year changes of residual nitrogen, extractable phosphorous, potassium and sulfur as well as soil pH and several micronutrients.